一、基本情况
温学森,1965.02出生,博士,教授,生药学专业,药学专业学位硕士研究生导师。
联系电话:0531-88382028(办公室),13853191766(手机)。
电子信箱:x.s.wen@163.com。QQ:1093663218
二、研究领域
1.中药饮片炮制工艺及其炮制机理研究
中药必须经过炮制才能入药,炮制是传统中药制药技术,也是保障中药安全有效的关键环节。本研究主要通过对比炮制前后化学成分和药理活性变化,揭示传统炮制工艺的科学性和合理性,为提高中药饮片质量、开发新的炮制工艺奠定基础。
2.中药材产地加工工艺及其加工机理研究
新收获中药材需要产地加工,产地加工技术显著影响药材质量。本研究主要探讨产地加工工艺对药材质量的影响,为提高药材质量奠定基础。
3.中药新药和保健食品的研究与开发
根据市场需要,研究和开发现代中药新药和保健食品。
三、工作及学习经历
1987年于山东师范老员工物系获学士学位;
1990年于山东师范老员工物系获硕士学位;
1990.07-2000.07于原山东医科大学英国立博官方网站工作;
2000.07-至今于英国立博官方网站工作
(2002.06于北京大学英国立博官方网站获博士学位,2005.12-2009.6于公司开展博士后研究,2014.07晋升教授)。
四、教学工作
主要承担药学专业本科生《药用植物学》和《生药学》,以及研究生《现代中药新药研究与开发》的教学工作。
五、承担课题
国家中医药管理局,第四次全国中药资源普查——台儿庄区(2017-515),2.17-2019
中澳健康中心合作项目:Efficacy and action mechanisms of modified Liuwei Dihuang Wan in preventing menopausal osteoporosis,2018-2020
六、代表性文章
1. Zhang FF,Wen XS*, Lu YF, Luo SF, Lv C and Xian CJ. Effects of differently processed rehmannia roots on dexamethasone-induced side effects in rats. J Med Toxicol Res 2018, 1:1.
2. Shi CJ,Wen XS*, Gao HF, Liu ZH, Xu XK, Li LF, Shen T, Xian CJ. Steamed root of Rehmannia glutinosa Libosch (Plantaginaceae) alleviates methotrexate-induced intestinal mucositis in rats. Journal of Ethnopharmacology 183 (2016) 143 – 150
3. Li LF, Gao HF, Shi CJ,Wen XS*. 2015. Steam processing improves negative inotropic and chronotropic effects of rehmannia root on isolated toad and rat hearts. ICMB2015 Proceedings. World Scientific,ISBN:978-981-4719-80-3. pp:1125-1131.
4. Wei GD,Wen XS*. Characteristics and kinetics of catalpol degradation and the effect of its degradation products on free radical scavenging. Pharmacognosy Magazine, 2014; 10: S122-129.
5. Zhu BM, Wei GD,Wen XS*. Effect of pretreatments on drying characteristics of Chinese jujube (Zizyphus jujuba Miller). International Journal of Agricultural and Biological Engineering, 2014; 7(1): 94-102
6. Sun YJ,Wen XS*, Zhao Y, Shen T, Liu ZH, Gao HF, Qiu SB, Chen Y. Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats. Journal of Ethnopharmacology, 2013; 150: 514–520.
7. Guo YX,Wen XS*, Zhao Y, Wei GD, Sun P. Maillard reaction contributing to chemical changes during the processing of Shu Dihuang, the steamed root of Rehmannia glutinosa. Asian Journal of Traditional Medicines, 2012; 7(2): 50-58.
8. Qin S,Wen XS*, Shen T, Xiang L. Thin layer drying characteristics and quality evaluation of steam blanched chrysanthemum. Transactions of the CSAE, 2011; 29(6): 357-364.
9. Zhang D,Wen XS*, Wang XY, Shi M, Zhao Y. Antidepressant effect of Shudihuang on mice exposed to unpredictable chronic mild stress. Journal of Ethnopharmacology, 2009, 123(1):55-60.