Dr. Lan Xiang
Corresponding Address：Institute of Pharmacognosy, School of Pharmaceutical Sciences, Shandong University, Jinan, 250012, China
Phone: 86-531-88382028(O)
E-mail: xianglan02@sdu.edu.cn
Course Taught
Pharmacognosy; Medicinal botany; Plant diet and health.
Research Field
1. Bioactive constituents of Traditional Chinese Medicine and their action mechanism
2. Quality control of Traditional Chinese Medicine
Studing and Working Experience
1990.09 ~ 1994.07 B.S.in Medicinal Botany, Department of Chinese Medicinal Material,
Jilin Agricultural University
1994.09 ~ 1995.07 Assistant Researcher, Department of Chinese Medicinal Material,
Jilin Agricultural University
1995.09 ~ 1998.07 M.S., Department of Chinese Medicinal Material,
Jilin Agricultural University
1998.09 ~ 2001.07 Ph.D., Department of Pharmacognosy, School of Pharmaceutical Sciences,
Peking University
2001.12 ~ 2003.12 Postdoctor, Department of Biological Science and Biotechnology,
Tsinghua University
2004.01 Lecturer, School of Pharmaceutical Sciences, Shandong University
2005.09 Associate Professor, School of Pharmaceutical Sciences, Shandong University
2008.06 ~ 2009.06 Visiting Scholar, Department of Psychiatry and Behaviour Science,
School of Medicine, Johns Hopkins University, USA
2011.12 Professor, School of Pharmaceutical Sciences, Shandong University,
Main Publication
Xiang L, Gao YH, Liu DY, Yang MH. Rapid determination of patulin in medicinal hawthorn fruits by HPLC-MS/MS. World Mycotoxin Journal, 2012, 5(1): 31-36.
Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Qi Peng, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KLK, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W. Neuroprotective role of Sirt1 in mammalian models of Huntington’s disease through activation of multiple Sirt1 targets. Nature Medicine, 2011, 18(1): 153-158.
Liu DY, Shen T, Xiang L. Two antioxidant alkaloids from Portulaca oleracea L.. Helvetica Chimica Acta, 2011, 94: 497-501.
Jiang M, Porat-Shliom Y, Pei Z, Cheng Y, Xiang L, Sommers K, Li Q, Gillardon F, Hengerer B, Berlinicke C, Smith WW, Zack DJ, Poirier MA, Ross CA, Duan W. Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism. Journal of Neurochemistry, 2010, 114(2): 419-429.
Liu DY, Zhao GW, Xiang L. Diverse strategies for the synthesis of the indoline scaffold. European Journal of Organic Chemistry, 2010, 21: 3975-3984.
Yang ZJ, Liu CJ, Xiang L, Zhen YN. Phenolic alkaloids as a new class of antioxidants in Portulaca oleracea. Phytotherapy Research, 2009, 23(7):1032-1035.
Xing J, Lv BB and Xiang L. Rapid screening for cyclo-dopa and diketopiperazine alkaloids in crude extracts of Portulaca oleracea L. using liquid chromatography/ tandem mass spectrometry. Rapid Communication Mass Spectrom, 2008, 22: 1415-1422.
Xiang L, Xing DM, Lei F, Wang W, Xu LZ, Nie L, Du LJ. Effects of season, variety and processing method on ellagic acid content in pomegranate leaves. Tsinghua Science and Technology, 2008, 13(4): 460-465.
Xiang L, Xing DM, Wang W, Ding Y, Du LJ. Alkaloids from Portulaca oleracea L.. Phytochemistry, 2005, 66(21): 2595-2601.
Xiang L, Lei F, Xing DM, Wang W, Zheng JH. Neuron protective constituents from Rheum nanum and Rheum sublanceolatum. Tsinghua Science and Technology, 2005, 10(4): 426-429.
Xiang L, Liu XH, Fan GQ, Cui YX, Du LJ, Zheng JH. Two new constituents from Rheum sublanceolatum. Journal of Asian Natural Products Research, 2005,7(4): 627-632.
Fan Lei, Dongming Xing, Lan Xiang, Lijun Du. Pharmacokinetic study of ellagic acid in rat after oral administration of pomegranate leaf extract. Journal of Chromatography B, 2003,796: 189-194.
Xiang L, Fan GQ, Li JH, Kang H, Yan YL, Zheng JH, Guo DA. The application of an artificial neural network in the identification of medicinal rhubarbs by near infrared spectrum. Phytochemical Analysis, 2002, 13(5): 272-276.
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