Lei Wang, Ph.D.
Institute of Pharmaceutical Analysis

School of Pharmaceutical Science

Shandong University

No.44, Wenhuaxi Road,

Jinan, 250012 P.R.China

Tel. 086-531-88363888 / 86-531-88382330

E-mail: wangl-sdu@sdu.edu.cn

Professor

Institute of Pharmaceutical Analysis, School of Pharmacy

Tutor for graduates

EDUCATION

2008:Ph.D. in Analytical Chemistry, Shandong University, Jinan, China

2001:M.Sc. in Phytochemistry, Shandong Medical University, Jinan, China

1986:B.Sc. in Chemistry, Shandong University, Jinan, China

TEACHING EXPERIENCE

1986 – present:Shandong University, Jinan, China Institute of Pharmaceutical Analysis, School of Pharmacy

2010.4-2011.4:Visiting Scholar in the Biodesign Institute at Arizona State University, U.S.A.

RESEARCH INTERESTS:

1. Design and construction of novel fluorescence nanoprobe and its application in pharmaceutical analysis

2. Design of specific identification element and construction of drug fluorescence sensors

3. Fluorescence amplification technique and ultra-sensitive detection strategy of biological medicine based on DNA self-assembly

4. Single molecule detection and single cell analysis based on fluorescence micro-imaging technology

CHINA NATIONAL RESEARCH GRANTS:

1. Single molecule detection and high-throughput screening based on hybridization chain reaction，National Natural Science Foundation of China，2012.01-2015.12 ；

2. Detection of single molecules in live cell with quantum dots imaging. National Natural Science Foundation of China，2009.01-2011.12 ；

3. Real Time Differentiation Agonist and Antagonist in living cells by Single-Quantum Dot Tracking Natural Science Foundation of Shandong Province., 2006.1-2008.12

RECENT PUBLICATIONS:

Bo Fu, Jch Cao, W Jiang*, Lei Wang,*, A Novel Enzyme-free and Label-free Fluorescence Aptasensor for Amplified Detection of Adenosine. Biosensors and Bioelectronics., 2013, 44: 52-56

J Ma, Yh Chen, Zh Hou, L Wang*, W Jiang*, Selective and Sensitive Mercuric (ii) Ion Detection Based on Quantum Dots and Nicking Endonuclease Assisted Signal Amplification, Biosensors and Bioelectronics., 2013, 43: 84-87

Qw Xue, L Wang*, W Jiang*, A versatile platform for highly sensitive detection of protein: DNA enriching magnetic nanoparticles based rolling circle amplification immunoassay, Chem. Comm., 2012, 33: 3930-3932. Inside cover paper

Zhg Wang, Qw Xue, Wzh Tian, L Wang* and W Jiang*, Quantitative Detection of Single DNA Molecules on DNA Tetrahedron Decorated Substrates, Chem Comm, 2012, 48 (77): 9661 - 9663

Lp Wang, Chch Guo, B Fu, L Wang*， Fluorescence determination of DNA using gatifloxacin-europium (Ⅲ) complex, J Agr Food Chem，2011, 59(5):1607-1611

Gh Zhou, L Wang*, Yd Ma, Lp Wang, Yy Zhang, W Jiang*，Synthesis of a quinazoline derivative: A new 1-adrenoceptors ligand for conjugation to quantum dots to study 1-adrenoceptors in living cells, Bioorg & Med Chem Lett,2011, 21, 5905-5909 X Zhou, L Wang*, Applications of Single-particle tracking in living cells, Drug Discoveries & Therapeutics, 2010, 4（2）62-69

Chch Guo, Ad Lang, L Wang*, W Jiang, The co–luminescence effect of a europium (III) – lanthanum (III) – gatifloxacin – sodium dodecylbenzene sulfonate system and its application for the determination of trace amount of europium (III)，J Lumin, 2010, 130（4）:591-597

Chch Guo, L Wang*, Zh Hou, W Jiang*, Lh Sang; Micelle-enhanced and terbium-sensitized spectrofluorimetric determination of gatifloxacin and its interaction mechanism, Spectrochim Acta A, 2009, 72 (4) : 766-771

L Wang*, Chch Guo, Zhj Chu, W Jiang*; Luminescence enhancement effect for the determination of balofloxacin with balofloxacin - europium (III) - sodium dodecylbenzene sulfonate system, J Lumin, 2009, 129（1）: 90-94